Recruiting

Testing a Herbal Supplement for Knee and Hip Arthritis Pain

Plain-English translation of NCT07324746 on ClinicalTrials.gov ↗ · Source last updated January 2026 · Translation generated June 2026 · How we translate trials

This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.

What is this trial?

This trial is testing a dietary supplement containing Boswellia serrata, Curcuma longa, and Vitis vinifera to see if it can help reduce pain and improve function in people with osteoarthritis of the knee or hip. You would take the medication for 4 weeks, then switch to a placebo (a pill with no active ingredients) for another 4 weeks so researchers can compare how well the treatment works. Throughout the study, you'll complete questionnaires and simple physical performance tests to measure any changes in your symptoms.

Osteoarthritis causes chronic joint pain and stiffness that significantly affects quality of life. This trial exists to find out whether this herbal combination might offer a natural option to help manage these symptoms.

Do you qualify?

You likely qualify if…

you are 18 years or older
you have been diagnosed with osteoarthritis in your knee or hip
you experience significant pain (at least 4 out of 10 on a pain scale) during your most painful movement
you have functional limitations from your arthritis (a score of 7 or higher on a standard assessment)
you are able to walk and move around, even if it's limited by pain

You likely don't qualify if…

you are pregnant or breastfeeding
you have autoimmune diseases like rheumatoid arthritis, lupus, or gout
you have had recent joint trauma, injury, infection, or previous joint injections with steroids in the last 12 months
you have an allergy to any of the herbal ingredients or to NSAIDs (over-the-counter pain relievers)
you have a history of stomach ulcers, serious gastrointestinal bleeding, liver or kidney problems, or cancer

What participation looks like

You would participate for 8 weeks total. For the first 4 weeks, you'll take the herbal supplement daily, and for the next 4 weeks, you'll take a placebo pill—neither you nor the researchers will know which is which at first. Throughout the study, you'll complete online questionnaires 6 times and perform 3 simple physical tests (like walking or climbing stairs) also 6 times to track any changes in your pain and movement. You'll also provide one urine sample.

AI-generated summary from trial data · Jun 6, 2026 · Not medical advice

Trial locations(1 site)

United Kingdom

Middlesex Univeristy London, London