Plain-English translation of NCT07328191 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing a new way to decide when people with advanced blood cancers need blood transfusions. Instead of following fixed blood count numbers, doctors would give transfusions based on how you're actually feeling and functioning day-to-day. The study wants to see if this approach can safely reduce the number of transfusions you need while keeping your quality of life just as good.
People with advanced blood cancers often need regular blood transfusions, but getting too many transfusions can cause side effects and take a toll on daily life. Researchers want to know if paying attention to how patients actually feel—rather than just blood numbers—could help doctors give transfusions more thoughtfully and reduce unnecessary ones.
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You would be randomly assigned to one of two groups: one following the standard transfusion approach (based on blood counts), and the other receiving transfusions guided by changes in your quality of life (measured by a brief questionnaire you'd complete regularly). You would attend scheduled visits to complete quality-of-life assessments, receive transfusions as directed by your assigned strategy, and have your overall well-being monitored throughout the study. The goal is to see whether the quality-of-life approach works just as well while potentially reducing the number of transfusions you need.
AI-generated summary from trial data · Aug 5, 2026 · Not medical advice
France
Sponsor
Centre Hospitalier Universitaire de Nice
Enrollment target
~52 participants
Started
February 2026
Primary completion
February 2027
Age range
18 Years and older
Last updated on clinicaltrials.gov in February 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Thomas Cluzeau, Professor
Centre Hospitalier Universitaire de Nice
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.