Lower versus standard radiation dose after initial cancer treatment

This trial is testing whether patients with advanced nasopharyngeal cancer can be treated with lower radiation doses instead of the standard dose, after they've already received chemotherapy and immunotherapy. The study will compare two groups: one receiving reduced radiation and one receiving conventional radiation, both combined with ongoing chemotherapy and immunotherapy. Researchers want to see if the lower dose works just as well while causing fewer side effects like dry mouth, difficulty swallowing, and hearing loss.

Standard radiation therapy for nasopharyngeal cancer can cause serious long-term side effects that affect quality of life. This trial exists to find out if patients whose tumors have already shrunk significantly from initial treatment can be spared from the full radiation dose while still staying cancer-free.