Plain-English translation of NCT07329361 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing Platelet-Rich Plasma (PRP) injections for knee osteoarthritis — a condition where the cartilage in your knee gradually wears down, causing pain. Specifically, researchers want to compare two approaches: using PRP that has been frozen and stored versus using PRP that is injected right after it's collected from your own blood. The goal is to see if freezing PRP beforehand affects how well it reduces your pain and improves how your knee works.
Knee osteoarthritis is common and painful, and many patients want alternatives to surgery or long-term pain medications. PRP is a promising treatment because it uses your own healing factors to reduce inflammation, but doctors aren't yet sure whether freezing it for later use works just as well as using it immediately.
You likely qualify if…
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You would be randomly assigned to receive either frozen or fresh platelet-rich plasma injected directly into your knee. First, a small blood sample would be taken from your arm to create the PRP. Depending on which group you're in, the injection would happen either right away or after the PRP has been stored. You would then return for follow-up visits to report how much your pain has improved and how well your knee is functioning.
AI-generated summary from trial data · Aug 4, 2026 · Not medical advice
Spain
Sponsor
MiKS Hospital
Enrollment target
~60 participants
Started
December 2025
Primary completion
December 2027
Age range
40 Years – 85 Years
Last updated on clinicaltrials.gov in January 2026.
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