Plain-English translation of NCT07331987 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether probiotics—live beneficial bacteria—can help reduce anxiety and depression symptoms when taken together with escitalopram, a common antidepressant medication. You would be randomly assigned to receive either probiotics plus the medication or a placebo (inactive pill) plus the medication for three months. The researchers will measure changes in your mood, anxiety, sleep, and gut health to see if the probiotics make a real difference.
Recent research suggests that gut health and the bacteria in your digestive system may play a role in mental health. This trial exists to find out whether adding probiotics to standard antidepressant treatment could improve outcomes for people struggling with anxiety and depression.
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You would visit the research clinic to be screened and assessed. If accepted, you would take either probiotics or a placebo pill daily for three months, while also taking escitalopram as prescribed. During this time, the researchers would measure your anxiety, depression, and sleep using questionnaires and blood tests to look at your gut bacteria and related markers. After the three-month treatment period, there would be one more follow-up visit about a month later to check on your progress and any lasting effects.
AI-generated summary from trial data · Jul 5, 2026 · Not medical advice
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