Phase III Randomized International Open Label Clinical Trial of Treatment Intensification With Docetaxel Plus Apalutamide in Patients With Metastatic Hormone-sensitive Prostate Cancer Who Did Not Achieve a Deep PSA Response After Initial Treatment With Apalutamide: REINFORCE Trial.

Recruiting

Plain-English translation of NCT07333066 on ClinicalTrials.gov ↗ · Source last updated June 2026 · How we translate trials

Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.

Trial locations(56 sites)

France

CH Bayonne, Bayonne

Institut Bergonié, Bordeaux

CHP Brest - Pasteur, Brest

Hôpital Henri-Mondor, Créteil

GHM Cancérologie - Institut Daniel Hollard, Grenoble