Plain-English translation of NCT07334418 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
During a planned cesarean delivery, some women experience severe pain that doesn't respond to standard pain relief. This pilot study is testing two common approaches to help: either switching quickly to full anesthesia (where you're asleep), or trying intravenous sedation first before switching to full anesthesia if needed. Both are standard medical approaches—the study is comparing which works better and is easier to manage.
Some women feel unexpected severe pain during cesarean delivery even with standard anesthesia. Researchers want to understand the best way to quickly and safely help these women, and whether preventing these traumatic experiences might improve their mental health and recovery after delivery.
You likely qualify if…
You likely don't qualify if…
If you qualify and severe pain occurs during your cesarean delivery, you'll be randomly assigned to one of two groups: one receiving immediate full anesthesia, or another receiving intravenous sedation first (with conversion to full anesthesia if needed). You'll be checked on during your hospital stay and then followed up at visits or calls over the next 6 weeks to assess your recovery, pain levels, and overall well-being.
AI-generated summary from trial data · Jun 14, 2026 · Not medical advice
United States
Sponsor
University of Pennsylvania
Enrollment target
~600 participants
Started
April 2026
Primary completion
November 2027
Age range
18 Years and older
Sex
Female only
Last updated on clinicaltrials.gov in June 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Mark Neuman, MD
University of Pennsylvania
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.