Plain-English translation of NCT07334457 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers are studying how blood cells called platelets change when patients receive ECMO — a temporary machine that does the work of the heart and lungs. Scientists have discovered that platelets come in different types with different jobs, and these types may shift during ECMO treatment in ways that could explain some of the bleeding and clotting problems patients sometimes experience.
Patients on temporary heart-lung support machines often develop complications related to bleeding and blood clots, but doctors don't fully understand why. This study hopes that understanding how blood cells change during this treatment will help doctors prevent or better manage these complications in the future.
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As a participant, you would have blood samples taken to study your platelets — this happens as part of your routine care in the intensive care unit, so there are no extra visits or procedures beyond what you're already receiving. Researchers will analyze these blood samples to see how your platelet types change while you're on the heart-lung support machine.
AI-generated summary from trial data · Jun 25, 2026 · Not medical advice
France
Enrollment target
~75 participants
Started
March 2025
Primary completion
March 2027
Age range
18 Years and older
Last updated on clinicaltrials.gov in January 2026.
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Central contact
Charles TACQUARD, MD, PhD
University Hospital, Strasbourg, France
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.