Plain-English translation of NCT07337902 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This is a small pilot study comparing two common, over-the-counter pain medications—acetaminophen and ibuprofen—to see which one works better for period cramps in women with Crohn's disease. You'll try both medications over four menstrual cycles to help researchers understand which is more effective and safer for people with your condition. This pilot study will help prepare for a much larger study in the future.
Women with Crohn's disease often struggle with period cramps, but doctors don't yet have clear evidence about which everyday pain reliever is best and safest for this group. This study will help answer that question.
You likely qualify if…
You likely don't qualify if…
You'll start with one in-person screening visit at UNC Chapel Hill that includes blood work, a physical exam, and some surveys about your Crohn's disease and menstrual cycle. After that, everything happens at home over about four months. Before and during each of your next four menstrual cycles, you'll take either acetaminophen or ibuprofen for three days when your period cramps start, submit stool samples, and complete very short online surveys (under one minute each) about how the medication worked. At the end, you'll have a brief phone or video call with a researcher to share your feedback.
AI-generated summary from trial data · Aug 10, 2026 · Not medical advice
United States