Plain-English translation of NCT07341490 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
When someone suffers a severe acute brain injury, doctors need to confirm whether blood flow to the entire brain has completely stopped. This study compares two imaging methods—a CT scan with contrast dye and a traditional four-vessel angiogram—to see which one is better at confirming this condition. Both tests show blood flow patterns in the brain and help doctors make this critical determination.
Currently, doctors use a detailed angiogram (four-vessel angiography) as the standard test to confirm complete loss of brain blood flow. Researchers want to see if a newer CT imaging technique could be just as accurate but potentially faster and easier to perform in critically ill patients.
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If you meet the criteria, your medical team would arrange for you to receive both imaging tests—the CT scan and the traditional angiogram—to allow researchers to compare how well each one works. Both tests involve injecting contrast dye to visualize blood flow in your brain. Your participation helps doctors determine whether the newer CT method could become a reliable alternative for future patients in similar situations.
AI-generated summary from trial data · Aug 15, 2026 · Not medical advice
Sweden
Collaborators
Karolinska Institutet
Enrollment target
~50 participants
Started
January 2026
Primary completion
December 2028
Age range
18 Years and older
Last updated on clinicaltrials.gov in March 2026.
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Central contact
Peter C Rudberg, M.D. Ph.D.
Region Stockholm
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