Plain-English translation of NCT07341763 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This study is testing a non-invasive brain stimulation technique called high-frequency transcranial random noise stimulation (hf-tRNS) to see if it can help people with vision loss from retinitis pigmentosa, rod-cone dystrophy, or advanced glaucoma improve their ability to navigate and walk safely. The treatment involves applying a gentle electrical current to the back of your head for 20 minutes to stimulate the visual processing area of your brain. Researchers will measure whether this treatment helps you walk more confidently through an obstacle course and move around more independently.
Many people with vision loss struggle with orientation and mobility—the ability to navigate safely and move around independently. This trial aims to explore whether targeted brain stimulation might improve these skills and help people with constricted visual fields regain confidence in their daily movement and independence.
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You will visit the clinic three times over about two weeks. At your first visit, you'll have vision tests to confirm you're eligible. At visits two and three (48 hours apart), you'll receive 20 minutes of either active brain stimulation or placebo (sham) stimulation while seated. Before and at 2 minutes and 30 minutes after each stimulation session, you'll walk through an obstacle course designed to test your navigation and walking ability—using your white cane if you normally do, or walking naturally if you don't. The researchers will measure how safely and confidently you navigate the course.
AI-generated summary from trial data · Jul 7, 2026 · Not medical advice
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