Testing a New Heart Scan to Guide Treatment for Clogged Arteries

Plain-English translation of NCT07341932 on ClinicalTrials.gov ↗ · Source last updated April 2026 · Translation generated September 2026 · How we translate trials

This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.

What is this trial?

This study is testing whether a new heart scan called magnetocardiography (or MCG) can help doctors decide whether you need an invasive procedure or can manage your heart condition with medication alone. Right now, doctors make these decisions using older methods like stress tests and the degree of blockage seen on CT scans. The trial wants to know if this newer scanning technology can help avoid unnecessary procedures and improve your quality of life.

Many patients with partially clogged heart arteries don't actually need invasive procedures, but current methods sometimes recommend them anyway. This trial is testing whether the new scan can more accurately identify which patients truly need a procedure and which can safely manage their condition with medication and lifestyle changes, potentially reducing unnecessary procedures and costs.

Do you qualify?

You likely qualify if…

you are between 18 and 80 years old
you have been diagnosed with stable coronary artery disease
a CT scan of your heart shows at least one major artery that is 50–90% blocked
you have chest discomfort that occurs with physical exertion or stress and improves with rest (if your blockage is 50–69%)
you are willing to participate in follow-up visits and phone calls for one year

You likely don't qualify if…

you have had a heart attack, bypass surgery, or a prior procedure to open a blocked artery
you have very severe heart disease, including blockages in the main artery to your heart or all three major heart arteries
you have a heart rhythm problem like atrial fibrillation or frequent irregular heartbeats
you have metal implants such as a pacemaker, mechanical heart valve, or metal plates from orthopedic surgery
you have severe claustrophobia or a severe chest wall deformity

What participation looks like

You will be randomly assigned to either get the new magnetocardiography scan to guide your treatment, or receive standard care based on your current test results. Depending on which group you're in, your doctor will then recommend either an invasive procedure or medical management with medications. After enrollment, you'll receive phone follow-up calls at 90 days, 6 months, and 1 year to check on how you're doing, any heart problems you've had, your symptoms, and healthcare costs. The study will last one year.

Testing a New Heart Scan to Guide Treatment for Clogged Arteries

What is this trial?

Do you qualify?

What participation looks like

Trial locations(5 sites)