Plain-English translation of NCT07342881 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 1 — Testing in a small group (usually 20–80 people) to find a safe dose and watch for side effects.
This is an early-stage study testing a new medication called pevifoscorvir sodium to see how it works in people with chronic hepatitis B. The researchers want to understand how the body processes this medication, especially in people whose kidneys aren't working as well as they should. This information will help doctors figure out if the medication is safe and whether dose adjustments are needed for different patients.
When your kidneys don't work well, medications can build up in your body and cause problems. Before this medication can be used widely, researchers need to understand how it behaves in people with kidney disease so they can prescribe it safely.
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You would visit the study clinic and take a single 100-milligram dose of the medication by mouth. The researchers will then monitor you closely with blood tests and heart monitoring over the next 14 days to see how your body processes the medication and whether you have any side effects. You'll need to avoid alcohol during this time and return for follow-up visits so the study team can track how you're doing.
AI-generated summary from trial data · Jun 6, 2026 · Not medical advice
United States