Can a probiotic supplement prevent colic and excessive crying in newborns?

This trial is testing whether Limosilactobacillus reuteri, a type of probiotic (beneficial bacteria), can help prevent colic and excessive crying in newborns when given starting in the first week of life. Researchers have seen promising results with this medication in other studies, and this trial will test whether it is safe and effective when given to healthy newborns for the first three months of their lives.

Many newborns experience excessive crying and colic, which can be very stressful for parents and families. Recent research suggests that this medication may help reduce these symptoms, but more testing is needed to confirm whether starting treatment very early in life—even before colic develops—can prevent the problem from happening in the first place.