Plain-English translation of NCT07347860 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 1 — Testing in a small group (usually 20–80 people) to find a safe dose and watch for side effects.
This early-stage trial is testing a new medication called in people with active rheumatoid arthritis (RA) that hasn't improved with at least two different standard treatments. is a special antibody designed to target and reduce harmful B cells—immune cells that drive RA inflammation—while activating other immune cells to help control the disease. The study will evaluate whether this medication is safe and how well it works for people whose RA has been difficult to control.
Many people with RA don't improve enough with currently available treatments, leaving them in pain and at risk of permanent joint damage. This trial explores whether a new approach—targeting specific immune cells in a different way—might help patients whose arthritis has been resistant to other therapies.
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You would receive injections of the medication under your skin over a 4-week treatment period, starting with a lower dose that may increase. The trial is enrolling a small group of 12–18 participants total to carefully evaluate safety and early signs of benefit. You would attend study visits for check-ups, blood tests, and assessments of your joint symptoms to see how the medication affects your arthritis.
AI-generated summary from trial data · Jun 5, 2026 · Not medical advice
China
Phase
Safety & dosing
Sponsor
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Collaborators
ITabMed Co., Ltd.
Enrollment target
~12 participants
Started
January 2026
Primary completion
August 2027
Age range
18 Years – 70 Years
Last updated on clinicaltrials.gov in January 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Qiubai Li Professor, 85726808
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.