Plain-English translation of NCT07352514 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This trial is testing whether a combination of two natural supplements—palmitoylethanolamide (PEA) and Scutellaria—work better together with therapeutic exercise to reduce nerve pain caused by chemotherapy. Nerve damage affecting the hands, feet, and other areas is a common side effect of cancer treatment, and this study wants to see if this medication, combined with a structured exercise program, can help ease that pain and improve how your nerves function.
Nerve damage from chemotherapy affects 30 to 60% of cancer patients and can cause lasting pain and disability. Currently, treatment options are limited, so researchers want to explore whether this medication combined with exercise might offer a better, more natural way to manage these symptoms.
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You would join one of three groups: one receiving the supplements plus exercise, one doing exercise only, or one taking the supplements only. Over several months (April to September 2025), you would receive your assigned treatment and be monitored to see how well it helps your nerve pain. The study tracks your symptoms and overall well-being during this time to compare which approach works best.
AI-generated summary from trial data · Jun 19, 2026 · Not medical advice
Italy
Sponsor
University of Palermo
Enrollment target
~40 participants
Started
March 2025
Primary completion
February 2026
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years and older
Last updated on clinicaltrials.gov in January 2026.
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Central contact
Giulia Letizia Mauro
University of Palermo
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