Plain-English translation of NCT07352761 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial studied three different surgical techniques to block the uterine arteries (blood vessels that supply the uterus) before removing fibroids through laparoscopic surgery—a minimally invasive approach using small incisions and a camera. The techniques tested were temporary clipping, temporary suturing, and permanent coagulation (heat sealing) of these arteries, compared against surgery without blocking them. The goal was to see if these blocking methods reduced bleeding during surgery and helped preserve ovarian function in women who wanted to maintain their fertility.
Uterine fibroids can cause severe bleeding, and fibroid removal surgery sometimes results in significant blood loss that may require transfusion. This trial investigated whether blocking blood vessels before surgery could safely reduce bleeding while preserving the ovaries' ability to function normally—an important concern for women who want to have children in the future.
Participants were randomly assigned to one of four groups: one group received temporary clipping of the uterine arteries before surgery, another received temporary suturing, a third had permanent heat-sealing of the arteries, and a control group had surgery without any artery blocking. All participants underwent laparoscopic fibroid removal surgery. Researchers then measured blood loss during the procedure, checked blood levels afterward, and monitored the health of the ovaries to ensure they continued working normally.
AI-generated summary from trial data · Jul 16, 2026 · Not medical advice
Egypt