Nerve Stimulation Treatment for Menstrual Cramps in Young Women

Plain-English translation of NCT07352982 on ClinicalTrials.gov ↗ · Source last updated January 2026 · Translation generated August 2026 · How we translate trials

This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.

What is this trial?

This trial is testing a treatment called transcutaneous tibial nerve stimulation (TTNS) for women with painful menstrual cramps. TTNS works by gently stimulating a nerve in your ankle to help reduce the pain signals your body sends during your period. You would receive this treatment alongside your regular pain medication to see if it helps more than medication alone.

Menstrual cramps affect many young women and can be severe enough to interfere with daily life. While pain medication helps, researchers want to see if this new treatment can reduce cramp pain even more by rebalancing the nerve signals that control your uterus.

Do you qualify?

You likely qualify if…

you are between 20 and 25 years old
you have been diagnosed with primary dysmenorrhea (menstrual cramps without an underlying disease)
you have regular menstrual cycles
you experience menstrual pain in your lower belly, lower back, or thighs during at least half of your cycles or in your last 3 cycles
your body mass index (BMI) does not exceed 30

You likely don't qualify if…

you have a gynecological condition or disorder (like endometriosis or fibroids)
you are taking birth control pills or have an IUD implanted
you have bleeding disorders, severe mental health conditions, active cancer, or nerve damage in your lower legs
you are currently smoking or taking sedative medications
you have had surgery, childbirth, or an ankle injury in the last 6 months

What participation looks like

You would visit the clinic three times per week for four weeks. At each visit, you would receive either real or placebo nerve stimulation at your ankle (you won't know which), and you'll continue taking your regular pain medication as you normally would. The researchers will track your pain levels before, during, and after the four-week treatment period to see if the nerve stimulation makes a difference.

AI-generated summary from trial data · Aug 22, 2026 · Not medical advice

Trial locations(1 site)

Egypt

Kafrelsheikh University (Faculty of Physical Therapy), Kafr ash Shaykh, Kafrelsheikh