Plain-English translation of NCT07354061 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 1/2 — A combined trial that checks safety and dosing while also starting to look at whether the treatment works.
This trial is testing whether a medication called ensartinib, when combined with standard chemotherapy, can help people with a specific type of advanced lung cancer before they have surgery. The goal is to shrink the tumor before an operation, which may improve long-term survival and quality of life. This is an early-stage study with about 20 participants.
Surgery alone for advanced lung cancer doesn't always lead to long-term survival, even when successful. While chemotherapy before surgery helps somewhat, doctors want to find more effective treatments to better prepare patients for surgery and improve their chances of staying cancer-free longer.
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You would receive the new medication combined with standard chemotherapy infusions over several weeks before your scheduled lung cancer surgery. During this time, you'll have regular clinic visits, blood tests, and imaging scans to monitor how well the treatment is working and how you're tolerating it. After completing the medication and chemotherapy, you would proceed to surgery as planned.
AI-generated summary from trial data · Jul 21, 2026 · Not medical advice
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