How fitness and immune therapy affect cancer treatment outcomes

This research study is tracking people with advanced cancer who are receiving immune checkpoint inhibitors—a type of cancer therapy that helps the body's immune system fight the disease. Researchers want to understand how physical fitness, side effects, and quality of life change during this treatment, and whether fitness levels affect how well people tolerate the medication and respond to it.

While immune checkpoint inhibitors have become an important cancer treatment, doctors don't yet fully understand how this medication affects a person's physical fitness or whether fitness levels predict who will do better with treatment and have fewer side effects. This study aims to fill that gap so that exercise and fitness could eventually become part of cancer care.