Plain-English translation of NCT07356310 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This research study uses a non-invasive breathing test called oscillometry to measure how easily air moves through your airways. Researchers want to understand whether airway resistance is connected to how your body responds to a methacholine challenge test (a standard test that checks how sensitive your airways are) and whether your body composition plays a role in these findings.
Many people with breathing problems and obesity may have airway sensitivity that isn't easily detected with standard tests. This study aims to find better ways to measure airway function and understand how body weight might affect asthma diagnosis and treatment.
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You would be asked to complete breathing tests during your visit, including the oscillometry test (which measures airway resistance as you breathe gently into a machine) and the standard methacholine challenge test you were already referred for. The study collects information about how your body composition relates to your breathing test results. There is no medication to take — this is purely observational testing to gather data about your airways.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
United States
Enrollment target
~100 participants
Started
February 2026
Primary completion
July 2027
Age range
18 Years and older
Last updated on clinicaltrials.gov in April 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Patrick Donohue, MD
University of Rochester
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.