Blood test to monitor Hodgkin lymphoma treatment in young people

Researchers want to see if a blood test that detects tumor DNA can help doctors better understand how well treatment is working for young people with Hodgkin lymphoma. Right now, doctors use imaging scans and other tests, but they aren't perfect at predicting who will respond well to treatment. This study will collect blood samples at different points during standard treatment to see if this new blood test could be a better, non-invasive way to monitor the disease.

Some young patients with Hodgkin lymphoma don't respond well to standard treatment or relapse after treatment ends, but doctors don't have a good way to identify these high-risk patients early. This blood test could give doctors real-time information about how the tumor is responding, potentially helping them adjust treatment sooner — either by intensifying it for those who need it or reducing side effects for those doing well.