Plain-English translation of NCT07360925 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Heart Failure research guide →Researchers are studying tissue samples from hearts that are being removed during heart transplant surgery. They want to understand how inflammation spreads between the fat tissue surrounding coronary arteries and the artery walls themselves. By examining these samples closely, scientists hope to learn more about how heart disease develops and progresses.
Heart failure and coronary artery disease remain leading causes of death worldwide. Better understanding how inflammation spreads in failing hearts could lead to new treatments and help doctors predict which patients are at highest risk.
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Your participation happens during your scheduled heart transplant surgery. Researchers will obtain small samples of your coronary arteries and surrounding fat tissue at the time your diseased heart is removed and replaced. Your medical history, age, weight, and current medications will also be recorded to help researchers understand the patterns they observe.
AI-generated summary from trial data · Jul 10, 2026 · Not medical advice
Czechia
Enrollment target
~60 participants
Started
June 2023
Primary completion
July 2028
Age range
30 Years – 90 Years
Last updated on clinicaltrials.gov in January 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Ivana K Lesna, MD, PhD., assoc. prof.
Institute for Clinical and Experimental Medicine
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.