Plain-English translation of NCT07361471 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Ovarian Cancer research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
Researchers are trying to understand why some ovarian cancer patients respond very well to platinum-based chemotherapy (the standard first treatment for ovarian cancer) while others' cancers continue to progress despite receiving the same medication. By studying tissue samples and genetic information from two groups of patients—those who stayed cancer-free for at least 5 years and those whose cancer progressed quickly—scientists hope to identify biological markers that could help predict who will benefit most from this treatment.
Currently, doctors cannot reliably predict which patients will respond well to platinum-based therapy and which won't. Understanding the genetic and biological differences between these two groups could help personalize treatment decisions and improve outcomes for future patients with ovarian cancer.
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If you qualify, you will not need to undergo new procedures or visits. Instead, researchers will use tissue samples that were already collected during your original cancer diagnosis and stored at the center. They will perform genetic and molecular tests on these existing samples to compare patterns between patients who responded well to treatment and those who did not. The study may also involve reviewing your medical records to gather clinical information about your treatment and outcomes.
AI-generated summary from trial data · Jun 9, 2026 · Not medical advice
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