Plain-English translation of NCT07365527 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing a procedure called contrast-enhanced ultrasound (CEUS)—a special type of ultrasound using sound waves and a contrast dye—to see if it can help change the way liver tumors respond to treatment. Researchers want to know if this approach is safe and can improve how the body's immune system fights colorectal cancer that has spread to the liver. You would receive either a lower or higher intensity version of this ultrasound treatment on one of your liver tumors.
Colorectal cancer that spreads to the liver is hard to treat, and doctors are looking for new ways to help patients. This trial explores whether sound waves can make tumors more responsive to treatment by changing the tumor's environment and boosting the body's immune response.
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If you join this trial, you will be randomly assigned to receive either a gentler or stronger version of the ultrasound treatment focused on one of your liver tumors. The procedure uses sound waves and a contrast dye injected into your bloodstream—similar to a regular ultrasound, but with added intensity. At least seven days after your treatment, doctors will take a small tissue sample (biopsy) from the treated tumor to see how it has changed. Researchers will then compare your results to other patients' tumors to understand whether the treatment changes how the immune system responds to cancer.
AI-generated summary from trial data · Jul 11, 2026 · Not medical advice
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