Plain-English translation of NCT07368842 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers want to understand whether analyzing hair can serve as a new way to measure metabolic health in people with severe obesity. This study will collect hair samples from 30 people scheduled for weight-loss surgery and compare them to 30 people with healthy weight. The researchers will track changes in the hair samples over 6 months after surgery to see if hair analysis can help doctors better understand obesity-related metabolic problems.
People with severe obesity often have metabolic problems that are difficult to detect early. Researchers believe that analyzing hair might reveal important information about metabolism and metabolic health, offering doctors a simpler, non-invasive way to monitor these conditions compared to current blood tests and other methods.
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If you are in the healthy-weight group, you will visit once for about 1–2 hours. You'll answer questions about your diet and quality of life, have your body measured, provide a hair sample, have photos taken of your scalp, and complete a muscle strength test. If you have severe obesity, you'll have the same baseline visit, then return three more times over 6 months after your weight-loss surgery to repeat these same procedures so researchers can see how your hair changes after surgery.
AI-generated summary from trial data · Jun 25, 2026 · Not medical advice
Singapore
Sponsor
Singapore General Hospital
Enrollment target
~60 participants
Started
February 2026
Primary completion
February 2028
Age range
21 Years – 70 Years
Last updated on clinicaltrials.gov in February 2026.
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Central contact
Hong Chang Tan, MD PhD
Singapore General Hospital
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