Testing a pain medication for sickle cell crises in children

This trial is testing whether ketamine, given at a low dose through an IV, can help relieve pain in children and young adults with sickle cell disease who are experiencing a sickle cell pain crisis. You would receive the medication along with your normal pain medicine, and the study team would compare how well it works compared to standard treatment alone. The goal is to find better ways to manage the severe pain that comes with sickle cell disease.

Sickle cell disease causes sudden, severe pain crises that can be very difficult to treat with standard pain medications alone. Researchers want to know if this medication, when used as an add-on treatment, can reduce pain more effectively and help patients feel better faster during these crises.