Plain-English translation of NCT07369908 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This research explores transcutaneous auricular vagus nerve stimulation (taVNS)—a non-invasive technique that applies gentle electrical stimulation to a specific part of the ear—to see if it can help reduce anxiety and improve how people regulate their emotions. Researchers will use brain imaging, heart rate monitoring, and behavioral tasks to understand how this treatment works in the brain and whether it's truly effective.
Early evidence suggests this ear stimulation may help with anxiety and emotional control, but scientists don't yet understand the underlying mechanisms—how it actually works in the brain. This study aims to fill that gap by combining advanced brain imaging with behavioral measurements.
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You'll visit the laboratory once for a session lasting several hours. First, you'll complete personality questionnaires (about 30 minutes), then undergo brain imaging scans while resting and while viewing emotional images. During the session, you'll receive either real ear stimulation or a sham (placebo) stimulation for 15 minutes, and you'll be asked to practice emotional regulation strategies on images shown to you. Throughout, researchers will monitor your heart rate, skin response, and collect saliva samples to measure stress hormones.
AI-generated summary from trial data · Jun 11, 2026 · Not medical advice
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