Plain-English translation of NCT07379138 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Melanoma research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This study is following people who have been treated for stage III or IV melanoma to understand how they're doing emotionally and physically during the first two years after treatment. Researchers are also testing whether a type of therapy called cognitive behavioral therapy for cancer distress (CBT-C) can help people cope with stress, sleep problems, and other challenges that come after a cancer diagnosis.
More people are surviving melanoma thanks to better treatments, but doctors don't have enough information about what life is really like for these survivors or how best to support their mental health and overall well-being during recovery. This study aims to fill that gap and find out whether the new therapy approach can truly make a difference.
You likely qualify if…
You likely don't qualify if…
All participants will complete questionnaires about their quality of life and mental health at the time they join and then every few months for two years. If you live in Minnesota, Iowa, or Wisconsin, you can optionally participate in the therapy part of the study, where you would either attend one therapy session per week for six weeks or receive standard care during that same period. The main questionnaire portion takes about two years, while the optional therapy sessions are just six weeks.
AI-generated summary from trial data · Jun 4, 2026 · Not medical advice
United States
Sponsor
Mayo Clinic
Enrollment target
~350 participants
Started
December 2025
Primary completion
December 2031
Age range
18 Years and older
Last updated on clinicaltrials.gov in January 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Clinical Trials Referral Office
Mayo Clinic
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.