Plain-English translation of NCT07379255 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Bladder Cancer research guide →This study is testing a new approach to choosing chemotherapy after bladder cancer surgery. Instead of using a standard chemotherapy plan for everyone, researchers will grow a small sample of your tumor cells in the laboratory and test how they respond to different chemotherapy drugs. This personalized approach may help doctors select the chemotherapy drugs most likely to work best for your specific cancer.
Advanced bladder cancer that has invaded deeply into the bladder wall or spread to lymph nodes has a poor outlook, even after surgery. Current treatment uses standard chemotherapy regimens that don't work equally well for everyone. This trial aims to see if tailoring chemotherapy to each patient's individual tumor response could improve survival rates and reduce unnecessary side effects.
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If you join the experimental group, your surgical tissue will be used to grow tumor cells in the laboratory, which will then be tested against seven different chemotherapy drugs over several weeks. Your personalized chemotherapy plan will be created based on these results. You will then receive the selected chemotherapy treatment as an outpatient and attend regular follow-up visits to monitor your response and side effects. The control group will receive standard chemotherapy based on typical treatment guidelines. Both groups will be followed for survival and disease progression.
AI-generated summary from trial data · Jun 13, 2026 · Not medical advice
China
Sponsor
Qilu Hospital of Shandong University
Collaborators
The Second Hospital of Shandong University, Qianfoshan Hospital
Enrollment target
~266 participants
Started
January 2025
Primary completion
December 2030
Age range
18 Years – 80 Years
Last updated on clinicaltrials.gov in January 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Jun Chen
Qilu Hospital of Shandong University
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.