Plain-English translation of NCT07380451 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing a new way to deliver psychotherapy for people with depression who also struggle with emotional regulation, relationship difficulties, or a history of early-life trauma. Instead of one standard treatment, the therapy is customized — you receive a core depression treatment plus additional short therapy modules chosen specifically for your needs. The goal is to help people whose depression hasn't improved well with usual care.
Many people with depression also have deep-rooted struggles with emotions, relationships, or past trauma, and they often don't improve as well with standard therapy. This study exists to see whether tailoring therapy to address each person's specific challenges leads to better outcomes within public mental health services.
You likely qualify if…
You likely don't qualify if…
If you are randomly assigned to the new treatment, you will receive weekly individual therapy sessions with a trained therapist. Your therapy will include core depression treatment strategies plus additional short modules targeting your specific needs — such as emotion regulation, relationship sensitivity, or social functioning — chosen based on your clinical profile. If assigned to usual care, you will receive standard individual psychotherapy as normally offered at your community mental health center. Either way, you will complete assessments at the beginning and end of treatment to measure changes in your depression, emotions, and relationships.
AI-generated summary from trial data · Jun 26, 2026 · Not medical advice
Chile