Plain-English translation of NCT07381621 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This trial is testing two different injection treatments for knee osteoarthritis — a common condition that causes chronic pain and stiffness. One group will receive perineural 5% dextrose injections, while another group will receive local anesthetic injections. Both are minimally invasive treatments that aim to reduce pain by targeting the nerves around the knee joint.
Knee osteoarthritis affects millions of people and causes long-term pain that can limit daily activities. Although doctors use various treatments, many people still struggle with symptoms, so researchers want to compare these two injection approaches to see which works better in real-world practice.
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You will receive one of the two injection treatments as part of your regular care — your doctor will help you decide which based on your specific situation. After that, you'll come back for check-ups at 1 month, 3 months, and 6 months after your injection. At each visit, the research team will assess your pain using a simple scale, test your knee's range of motion, check your leg strength, and ask about how well you're functioning in daily life.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
Turkey (Türkiye)