Testing inhaled nitric oxide to improve exercise ability in severe lung disease

This trial is testing inhaled nitric oxide, a gas that may help people with moderate-to-severe COPD breathe better and exercise with less difficulty. Researchers want to understand whether the medication is safe and whether it truly improves how far people can walk or how much physical activity they can do. The study will compare two different doses to see which works best.

People with severe COPD often struggle with exercise because their lungs don't work efficiently, which limits their quality of life and independence. This trial exists to explore whether this medication could be a new treatment option that safely helps patients exercise longer and feel less breathless.