Plain-English translation of NCT07385651 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing a new way to store donor kidneys before transplant surgery. Instead of the standard practice of storing kidneys on ice (4°C), researchers want to see if storing them at a slightly warmer temperature of 10°C can reduce damage to the organ and help it work better after transplant. Early studies in other organs like lungs show promising results with this warmer storage method.
One in four people who receive a deceased donor kidney experiences delayed kidney function after transplant, which means they need dialysis for a while and may have worse long-term outcomes. Researchers believe this happens because the cold storage on ice actually causes damage to the kidney cells. This trial is testing whether a slightly warmer storage temperature can reduce that damage and prevent these complications.
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If you are selected, your transplant surgery will proceed as usual, but your donor kidney will have been stored at the new warmer temperature instead of on ice. After surgery, you will have your urine collected and analyzed 24 hours after the transplant, and researchers will review your medical records to track how well your new kidney is working. The transplant itself follows standard clinical procedures.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
United States