Plain-English translation of NCT07386418 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
ORBITA-SOLAR is a diagnostic study that uses specialized heart catheterization procedures to measure exactly when and how chest pain (angina) develops in people with two coronary artery blockages. Researchers will gently inflate a small balloon in your coronary arteries while you exercise on a stationary bike, measuring blood flow pressure at each blockage site to determine your personal angina threshold — the point at which reduced blood flow triggers your symptoms.
Currently, doctors use standard measurements to decide which heart blockages need treatment, but these measurements don't account for the fact that different people develop chest pain at different levels of blood flow reduction. This study aims to discover whether each blockage has its own angina threshold, which could help doctors personalize treatment decisions and improve outcomes.
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You will undergo an invasive cardiac catheterization procedure in a specialized hospital lab. A thin tube will be inserted through an artery in your groin and threaded to your heart, where doctors will use a small balloon to temporarily reduce blood flow while you exercise on a stationary bike, measuring the exact pressures at which your chest pain develops. The entire procedure typically takes several hours, and you will be monitored closely throughout. After the procedure, you will have a brief recovery period before going home.
AI-generated summary from trial data · Jul 1, 2026 · Not medical advice
United Kingdom