Plain-English translation of NCT07387432 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether exercise can help smokers and ex-smokers protect their lung function and prevent chronic obstructive pulmonary disease (COPD), a serious long-term breathing condition. Participants will be randomly assigned to one of three groups: guided exercise with telehealth video classes, self-guided walking exercises, or a control group that receives no exercise instruction. Everyone will also receive advice about quitting smoking.
Many smokers develop a specific pattern of lung changes that can eventually lead to COPD. Researchers want to know if starting an exercise program early—before serious lung disease develops—can slow down or prevent this progression and help people breathe better.
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The study lasts about 18 months total: 6 months of active intervention followed by 12 months of follow-up. If you're assigned to the exercise-with-telehealth group, you'll attend online physiotherapy classes twice a week for one hour. If you're in the self-guided exercise group, you'll be encouraged to walk more each week, with goals that gradually increase. All participants will have breathing tests, walking tests, and check-ins at regular intervals (every 2–4 weeks initially, then less frequently), plus all groups will receive smoking cessation advice.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
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