Plain-English translation of NCT07392216 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Sickle Cell Disease research guide →Researchers at St. Jude Children's Research Hospital want to understand how sickle cell disease might affect young women's reproductive health—specifically, whether it changes the number or quality of eggs their ovaries produce. By comparing girls with sickle cell disease to healthy peers, they hope to learn whether this medication and disease-related damage is an issue that should be monitored as girls grow up.
Young women with sickle cell disease may face unique challenges to their fertility, but doctors don't yet have clear information about how common this problem is or when to watch for it. This study aims to fill that gap so doctors can better support women with sickle cell disease as they plan for their futures.
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You'll fill out a brief questionnaire once a year for up to two years (or just once if you're a healthy control), answering questions about your period, any hormonal medications, and your overall health. At routine clinic visits, the researchers will ask your doctors to collect an extra blood sample during lab work you're already getting for your regular care—no extra needle sticks needed. For healthy controls, there's one separate study visit to donate blood.
AI-generated summary from trial data · Jun 9, 2026 · Not medical advice
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