Plain-English translation of NCT07399587 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.
This trial is testing a treatment called BaroStim, a small device that stimulates a nerve in your neck to help your heart work better. You would receive this device after first having a heart pressure monitoring device (CardioMems) placed and spending 3 months adjusting your heart medications. The study team will then monitor how well the nerve stimulation helps improve your heart function and your ability to exercise over the next year.
Many people with severe heart failure struggle with shortness of breath and have very limited ability to exercise, even while taking multiple medications. This trial is testing whether BaroStim could provide an additional benefit by working with your medications and heart monitoring to help you feel better and live more actively.
You likely qualify if…
You likely don't qualify if…
You would have both the CardioMems and BaroStim devices placed in your body as part of standard care before the study officially begins. Then the study involves regular office visits over 1 year where the research team adjusts your BaroStim settings, checks your heart pressure readings, measures how far you can walk, and monitors your blood pressure and other vital signs. The goal is to find the best settings for your device to bring your heart pressure down to a healthy level and improve your exercise ability.
AI-generated summary from trial data · Aug 6, 2026 · Not medical advice
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