Plain-English translation of NCT07400653 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Obesity research guide →Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.
This is a major research study testing a new medicine called MET097 (also called ), which is a once-weekly injection for adults living with type 2 diabetes and excess weight. The medication is designed to help people lose weight and improve their blood sugar control. About two-thirds of participants will receive the medication, while one-third will receive a placebo (a shot with no active medicine) to help researchers understand how well the treatment really works.
Type 2 diabetes and excess weight often go together and can be difficult to manage with current treatments. This medication aims to address both problems at the same time by helping people lose weight while also bringing down their blood sugar levels.
You will visit the research clinic about 14 times over 21 months (roughly every 6 weeks), with 5 additional check-ins by phone. You'll learn to give yourself a weekly injection under your skin at home. During visits, the research team will check your weight, blood sugar levels, and overall health. You'll also check your blood sugar with a finger-stick test as instructed and report how you're doing on the medication.
AI-generated summary from trial data · Jul 12, 2026 · Not medical advice
United States