Plain-English translation of NCT07400991 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
When your heart isn't pumping well, your body can retain too much fluid, making breathing difficult and causing swelling. Right now, doctors usually ask heart failure patients to drink less fluid to help reduce this buildup. This trial is testing whether letting patients drink whenever they feel thirsty works just as well as—or better than—strictly limiting fluids, while keeping patients safe and improving how they feel.
Fluid restriction is hard for patients to follow when they're thirsty, and it may affect their quality of life. Researchers want to know if a more flexible approach—drinking when your body tells you to—could be equally effective and easier to live with.
You likely qualify if…
You likely don't qualify if…
You will be randomly assigned to either a thirst-driven group (drink when you feel thirsty) or a fluid-restriction group (limit how much you drink) while you're in the hospital and for one month after you go home. The study team will monitor your symptoms, measure your weight and blood work, and ask you about your thirst and quality of life to see how each approach affects you. The trial involves about 420 people total and will help doctors understand the best way to manage fluid in heart failure patients.
AI-generated summary from trial data · Jun 25, 2026 · Not medical advice
Denmark