Plain-English translation of NCT07402525 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is studying whether radiation therapy given after surgery can help prevent tongue cancer from coming back in patients who have early-stage disease with certain warning signs. You would be randomly assigned to either receive radiation therapy or to be carefully monitored without additional treatment. The study will compare how many patients stay cancer-free in each group over 3 and 5 years.
Doctors know that some early-stage tongue cancers have features that make them more likely to return even after surgery. This trial aims to find out whether giving radiation therapy after surgery helps prevent recurrence and whether the benefits outweigh any side effects.
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If you join this trial, you will have surgery to remove your tumor (which happens before enrollment). Then you will be randomly assigned to one of two groups: the radiation therapy group will receive radiation treatments starting 4 to 8 weeks after surgery, or the observation group will have regular follow-up appointments without additional treatment. Both groups will be monitored over several years to track whether the cancer returns, how you're doing, and any side effects you experience.
AI-generated summary from trial data · Aug 2, 2026 · Not medical advice
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