Plain-English translation of NCT07408453 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers want to understand how stress during pregnancy—both emotional stress and biological stress markers in the body—affects newborns born through fertility treatment like in vitro fertilization (IVF). By comparing pregnancies where the mother is genetically related to the baby with pregnancies where she is not (egg donor pregnancies), the study can separate the effects of prenatal stress from genetic factors.
Couples who use fertility treatments often experience high levels of stress during pregnancy, but we don't fully understand how this stress affects the baby's health and early development. This research aims to fill that gap.
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You and your partner would complete online questionnaires several times during your pregnancy asking about stress, mood, and support. In your third trimester, you would collect saliva samples at home over two days to measure stress hormones. At birth, the research team would record your baby's measurements and health status. The study follows you from early pregnancy through birth and is conducted entirely through your fertility center, with most data collection happening online.
AI-generated summary from trial data · Jun 20, 2026 · Not medical advice
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