Artichoke supplement and Mediterranean diet for diabetes prevention

This trial is testing whether a daily artichoke by-product supplement rich in specific plant compounds called hydroxycinnamic acids can help prevent type 2 diabetes when combined with a Mediterranean diet. Researchers want to see if the medication works better than diet and exercise alone at improving how your body uses insulin and managing your weight. The study will last 16 weeks, and participants will be randomly assigned to either receive the artichoke supplement or a placebo (dummy pill) while following the same healthy eating and exercise plan.

Type 2 diabetes and obesity are major health problems, and while Mediterranean-style diets have helped many people, results vary from person to person. This trial explores whether the medication might enhance the benefits of a healthy diet by addressing insulin resistance at a deeper level, and whether certain people might respond better to this treatment based on their individual biology.