How well does a blood filter remove toxins in severe infections

This trial is studying how well the Oxiris hemofilter — a special medical device that cleans the blood — removes harmful toxins and inflammatory substances in people with septic shock (a life-threatening infection). Right now, doctors often replace this filter every 12-24 hours because they worry it stops working well, but the study wants to find out if that's really necessary by measuring exactly how much the filter removes over a full 24-hour period.

Septic shock is a severe infection that can damage the kidneys and other organs, and this blood filter is designed to help remove the harmful toxins and inflammatory chemicals that make sepsis so dangerous. However, doctors don't fully understand how long the filter works effectively, so this study aims to provide clear evidence about whether the current practice of replacing it frequently is actually needed.