Recruiting

AI imaging system to identify eye problems in severe nearsightedness

Plain-English translation of NCT07424755 on ClinicalTrials.gov ↗ ·

What is this trial?

Researchers are building an intelligent computer system that combines three types of eye imaging — ultra-wide-angle photography, ultrasound, and detailed retinal scans — to better diagnose and track eye diseases in people with severe nearsightedness. The system aims to help doctors predict vision loss and catch problems earlier, so treatment can start sooner and be more personalized to each patient's needs.

Severe nearsightedness puts people at high risk for serious eye complications like cataracts, glaucoma, and vision loss. Currently, doctors don't have a reliable way to predict how quickly someone's vision will decline or to catch these problems at the earliest, most treatable stage. This new AI system could change that.

Do you qualify?

You likely qualify if…

you have been diagnosed with cataracts and severe nearsightedness (refractive error greater than 600 degrees)
you have posterior staphyloma, a specific eye condition related to severe nearsightedness
you have completed comprehensive eye exams including ultra-wide-angle photography, ultrasound imaging, and optical coherence tomography
you have complete medical records documenting your demographics, health history, and detailed eye measurements

You likely don't qualify if…

you have poor-quality eye imaging that prevents clear identification of eye structures
you have other serious eye diseases like glaucoma or diabetic eye disease
you have severe medical conditions that could interfere with the study results
you have significant media opacities or other eye conditions that complicate diagnosis

What participation looks like

You will have already completed the three types of eye imaging scans (ultra-wide-angle photography, ultrasound, and detailed retinal imaging) as part of standard care. Researchers will use these existing images and your medical records to help train and test the new AI system — you won't need to undergo additional procedures or visits for this study.

AI imaging system to identify eye problems in severe nearsightedness

What is this trial?

Do you qualify?

What participation looks like

Trial locations(1 site)