Plain-English translation of NCT07425730 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers are studying whether early heart problems can help identify children with lupus who have the most severe, hard-to-treat form of the disease. Some children with lupus don't respond well to standard treatments, and doctors currently don't have a reliable way to spot these children early. This study uses special heart ultrasound imaging to look for subtle heart changes that might signal severe lupus.
Even with the best available treatments, some children with lupus develop a severe form that keeps getting worse. Right now, doctors don't have an early warning sign to identify which children will struggle with severe disease. This study hopes to find that early heart changes could be that warning sign, so children at highest risk can be spotted sooner.
You likely qualify if…
You likely don't qualify if…
If you join this study, you will have heart ultrasound imaging done — a painless test using sound waves to look at how your heart is working. The researchers will collect information about your lupus and compare heart findings across all participants to see if early heart changes can predict who has severe lupus. The study is recruiting up to 60 children total.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
China
Enrollment target
~60 participants
Started
February 2026
Primary completion
July 2026
Age range
7 Years – 17 Years
Last updated on clinicaltrials.gov in April 2026.
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.