Plain-English translation of NCT07431398 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Sickle Cell Disease research guide →Phase 1 — Testing in a small group (usually 20–80 people) to find a safe dose and watch for side effects.
This is a Phase 1 study testing , an experimental medication being developed for sickle cell disease. Researchers want to understand how your body absorbs, processes, and eliminates this medication when taken as a single tablet dose. The study will help them decide the right way to give this treatment to patients in the future.
Before any new medication can be widely used, doctors need to understand how it moves through the body and how much of it reaches the bloodstream. This information is essential for determining safe and effective doses in future studies.
You would check into the clinic on Day 1 and stay overnight. On the morning of Day 2, after fasting for 10 hours, you would take a single tablet of the medication. Researchers would then collect blood samples over the next 72 hours to measure how your body processes it — you'd stay in the clinic for the first 48 hours and return for brief outpatient visits after that. The entire study lasts about 2 weeks from screening to final visit. (A second group of participants might also be tested after eating a large breakfast to see if food affects how the medication is absorbed.)
AI-generated summary from trial data · Jun 25, 2026 · Not medical advice
United States