Plain-English translation of NCT07432815 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Depression research guide →Phase 4 — The treatment has already been approved. Researchers are tracking how it works in a large number of people over time.
This study is testing whether combining (a medication commonly used to treat psoriasis) with an antidepressant called escitalopram works better than alone for people living with psoriasis and depression or anxiety. The researchers want to see if treating both the skin condition and the mental health symptoms together leads to better results for patients overall.
Many people with psoriasis also struggle with depression or anxiety, and these conditions can make each other worse. This trial exists to find out whether addressing both problems at the same time with this medication combination might help patients feel and look better than treating just the skin condition alone.
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You will be randomly placed into one of two groups: one taking the standard medication alone, or one taking the standard medication plus an antidepressant. You will take your assigned medication(s) for 6 months while researchers check on your skin, mood, and quality of life through regular visits and questionnaires. The study will measure how much your psoriasis improves and how your depression and anxiety symptoms change over that time.
AI-generated summary from trial data · Jun 5, 2026 · Not medical advice
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