Blood markers to predict how lung transplant rejection treatment works

This trial is studying whether certain markers in your blood can help doctors predict how well extracorporeal photopheresis (ECP) — a special blood treatment — is working for you. You're already being prescribed ECP by your doctor to treat chronic rejection after your lung transplant. This study simply asks you to give small blood samples at key points during your 6-month treatment cycle so researchers can look for signs that might show how your body is responding.

After a lung transplant, some patients develop chronic rejection, where the body gradually damages the new lungs over time. The medication ECP can help slow this process, but doctors don't yet have a reliable blood test to know early on whether it's working for each individual patient. This study hopes to find those predictive markers so treatment can be adjusted faster if needed.