Plain-English translation of NCT07436793 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial is testing whether giving patients a hormone medication called or micronized progesterone for about three weeks before their planned uterine cancer surgery can help shrink or slow down the cancer. Researchers want to understand how well these medications work and what signs in the tumor tissue show which patients benefit most from this treatment.
Endometrial cancer is often treated with surgery, but doctors want to find ways to improve outcomes and give patients the best chance for recovery. This study explores whether using a hormone medication before surgery—rather than waiting until after—might help fight the cancer more effectively.
You likely qualify if…
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You will start by having a small tissue sample taken from your uterus if you haven't had one recently. Then you will take one of two hormone medications by mouth twice daily (or once daily, depending on which group you're assigned to) for 21 to 24 days. After this period, you will have your planned surgery to remove your uterus, as you and your doctor already decided. About one to six weeks after surgery, you will have a follow-up visit to make sure you're recovering well.
AI-generated summary from trial data · Jul 4, 2026 · Not medical advice
United States